Indiana, the manufacturing center for the RV industry, was ranked as the best place to do business in the Midwest and the fifth best nationwide in the Pollina Corporate Top 10 Pro-Business States for 2012 study, co-published with the American Economic Development Institute. According to a news release, this is the fourth ranking in less than a year in which the Hoosier state’s business climate has scored a top 10 finish nationally.

The Pollina Corporate Top 10 Pro-Business States study, now in its ninth year, is based on 32 factors controlled by state government, including taxes, human resources, education, right-to-work legislation, energy costs, infrastructure spending, workers compensation laws, economic incentive programs and state economic development efforts. Indiana’s ranking in the report has moved up 18 places since 2010, earning it the title of “most improved state” this year.

“Indiana’s pro-business policies and solid fiscal house continue to earn national attention as a frontrunner for new jobs and investment,” said Dan Hasler, secretary of commerce and CEO of the Indiana Economic Development Corp. “This ranking is the latest validation of this administration’s focus since 2005 to make economic development efforts a top priority. Above all else, business climate matters and the payoff for Hoosiers is new careers and opportunities.”

Indiana’s fifth place ranking makes it the only Midwestern state and the only Northern state in the publication’s top 10. Among neighboring states, Kentucky ranked 28th, Ohio ranked 20th, Michigan ranked 39th and Illinois ranked 48th.